Complete Database
Browse our comprehensive collection of 84 compound profiles — peptides, hormones, pharmaceuticals, and longevity compounds with detailed protocols and references.
Showing 9 of 84 compounds
Glucophage · Fortamet
The world's most prescribed diabetes medication, now studied as a potential anti-aging drug through AMPK activation, mTOR inhibition, and mitochondrial effects.
Dose
500-1000 mg/day oral for longevity (men and women). Start at 500 mg with meals. Extended-release preferred to minimize GI effects.
Route
Oral tablet (immediate
Half-life
~6.2 hours
Sirolimus · Rapamune
The only compound proven to extend lifespan in every organism tested, from yeast to mammals, through inhibition of the mTOR pathway — the master regulator of cellular aging.
3-6 mg oral once weekly (longevity protocol, men and women). Typically cycled: 6 weeks on, 2 weeks off. Monitor bloodwork.
Oral tablet
~62 hours
Nicotinamide Mononucleotide · NMN
NAD+ precursors that restore declining cellular energy levels, activate sirtuins and PARPs, and support DNA repair — central to the biology of aging.
250-1000 mg/day NMN; 300-600 mg/day NR
Oral capsule/powder; sublingual; some IV NAD+ protocols
~2-3 minutes
Trans-Resveratrol · 3,5,4'-Trihydroxystilbene
A polyphenol compound found in red wine and grapes that activates SIRT1, enhances mitochondrial function, and provides cardiovascular and neuroprotective benefits.
250-1000 mg/day (trans-resveratrol); taken with fat for absorption
Oral capsule/powder
~1-3 hours
Elamipretide · Bendavia
A mitochondria-targeted tetrapeptide that restores cellular energy production by stabilizing cardiolipin, reversing age-related mitochondrial dysfunction within hours.
Research doses: 0.5-5 mg/day subcutaneously. Clinical trial doses: 4mg/day to 40mg/day (subcutaneous or IV). Common research protocol: 1-5 mg/day subcutaneous injection. Start at lower doses.
Subcutaneous injection (also studied IV in clinical settings)
~4 hours
Diaminodiphenyl Sulfone Analog · Dapsone Derivative
An anti-inflammatory and antioxidant compound studied for its potential to modulate aging pathways, reduce chronic inflammation, and support cellular health.
50mg-200mg
Oral
~12-24 hours
FOXO4-D-Retro-Inverso · Senolytic Peptide
A senolytic peptide that selectively induces apoptosis in senescent cells by disrupting the FOXO4-p53 interaction, effectively clearing 'zombie cells' that drive aging.
5mg
Subcutaneous injection
Methylthioninium Chloride · MB
A century-old pharmaceutical with remarkable mitochondrial-enhancing and neuroprotective properties, acting as an alternative electron carrier in the mitochondrial ETC.
5mg-25mg
~5-6 hours
NAD+ IV · NAD+ Injection
Direct injectable form of NAD+ that bypasses oral bioavailability limitations, rapidly restoring cellular NAD+ levels to support mitochondrial function, DNA repair, and sirtuin activation.
SubQ: 50-200mg daily. IV: 250-1000mg per session (infused over 2-4 hours)
~30-45 minutes